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1We sought to identify distinctive features of AML cells for universal MRD monitoring.
2Results demonstrated that VAS3947 induces apoptosis in AML cells independently of its anti-NOX activity.
3VEGF plays an important role in the abnormal proliferation and apoptosis of AML cells.
4No correlation between the level of CXCR4 expression on AML cells and engraftment was observed.
5Nevertheless, several studies indicate that AML cells show high levels of DNA lesions and genomic instability.
6Candidate Ara-C metabolizing gene expression in primary AML cells is proposed to account for this variation.
7In conclusion, this is the first report that monensin potently inhibits the proliferation of AML cells.
8Consistent with the observed mtDNA damage, bleomycin reduced mt mass and basal oxygen consumption in AML cells.
9Methods: We compared genome-wide gene expression of AML cells from 157 patients with that of normal myeloblasts.
10Here, we find that MYB protein binds within the regulatory region of the SKI gene in AML cells.
11We identified bleomycin as an agent that damaged mtDNA in AML cells at concentrations that induced cell death.
12Transient exposure to mebendazole is sufficient to inhibit colony formation by AML cells, but not normal cord blood-derived cells.
13AML cells may also home to the central nervous system and other solid organs such as cortical bone and skin.
14Together, our data describe a novel role for autocrine IGF-I signaling in the growth and survival of primary AML cells.
15In this study we demonstrate that erastin enhances the sensitivity of AML cells to chemotherapeutic agents in an RAS-independent manner.
16We found that BPTES only suppressed the growth of AML cells expressing mutant IDH compared with those expressing wild type IDH.
Esta colocação é formada por:
Aml cells nas variantes da língua
Estados Unidos da América