Significados de amyloid fibril em inglês

The formation of this protein network shares features with amyloid fibril formation.

The tetrapeptide KFFE is one of the shortest amyloid fibril-forming peptides described.

Oligomers are commonly observed intermediates at the initial stages of amyloid fibril formation.

Furthermore, the antibacterial mechanism of the lysozyme amyloid fibril hydrogels is initiated by membrane disintegration.

The process of amyloid fibril formation exerts a cytotoxic effect, resulting in tissue damage and organ dysfunction.

It is known that below pH 5 stefin B undergoes a conformational change and amyloid fibril formation.

Chronic hyperglycemia results in the formation of advanced glycation end-products (AGEs) and triggers amyloid fibril formation.

We show that copper binding inhibits the amyloid fibril formation and, to a lesser degree, the initial aggregation.

Diagnosis and treatment of systemic amyloidosis depend on accurate identification of the specific amyloid fibril protein forming the tissue deposits.

Together, our findings suggest that polyphenols could have a protective effect and the redirection can help alleviate the amyloid fibril formation.

Relative to PMCA, the amyloid fibril growth assay is less restrictive, but it did reflect certain properties of in vivo prion transmission.

The data support the hypothesis that amyloid fibril formation involves the ordered self-assembly of partially folded species that are critical soluble precursors of fibrils.

In addition, the in-register parallel β-sheet commonly observed for amyloid fibril structure does not apply to residues 11-24 in the 150-kDa oligomer.

We investigate how the molecular mechanism of monomer addition to a growing amyloid fibril of the transthyretin TTR105-115 peptide is affected by pH.

These results support that A(beta)1-42, the major pathogenic form in AD, may reach supersaturation and generate competent nuclei for amyloid fibril formation intracellularly.

However, the presence of amyloid fibrils in semen remained to be demonstrated.