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It is unlikely a vaccine will be achieved because of what we call antigenic drift and antigenicshift.
2
Recently, incidence has risen in countries with strong vaccine programmes and there are concerns about antigenicshift resulting in vaccine evasion.
3
Due to continuous antigenic drift and occasional antigenicshift, influenza viruses escape from human adaptive immunity resulting in significant morbidity and mortality in humans.
4
- There are two different ways: antigenic drift, which happens all the time, and antigenicshift, which only happens occasionally.