NanoOrange binds noncovalently with hydrophobic protein regions to form highly fluorescent complexes.

However, a mutation that reduced the hydrophobic contacts did inhibit dimer formation.

The structures produced include mono-functional hydrophobic and multi-functional amphiphilic core corona stars.

The structure revealed that the entire calmodulin-spectrin-binding interface is hydrophobic in nature.

Many previous studies have explored the interactions between MPs and hydrophobic pollutants.