Recent evidence suggests that cellular senescence also may be involved in aging.
2
EWS deficiency leads to impaired development and early senescence through unknown mechanisms.
3
It has been suggested that this process is responsible for cellular senescence.
4
However, the signaling mechanism linking obesity with age-related vascular senescence is unknown.
5
Premature and absolute loss of PTEN activity usually tends to cellular senescence.
1
An accelerated rate of biologicalaging could contribute to this increased risk.
2
Problem: Epigenetic age indices are markers of biologicalaging determined from DNA methylation patterns.
3
A widely used marker of biologicalaging is telomere length.
4
This study assessed the contribution of genetic and nongenetic factors to biologicalaging in American Caucasians.
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As the biologicalaging process demonstrates gender-specific characteristics, the analyses were performed separately in males and female.
Uso de biological ageing em inglês
1
He sees it as a matter of re-educating the public and health authorities to see biologicalageing in a new light.
2
Thus, drift emerges as a promising biomarker for premature or biologicalageing, and could potentially be used in geriatrics for disease risk prediction.