Heparin-induced thrombocytopenia refers to the decrease in bloodplateletcount following the administration of heparin, which is an anticoagulant.
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However, a low dose of cyclosporine A resulted in a sustained normal range of bloodplateletcount and negative proteinuria.
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Results: During treatment the leukocyte count decreased remarkably, and the patient developed lymphopenia together with a paradoxical increase in her bloodplateletcount.
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The low peripheral bloodplateletcount is caused by premature platelet destruction by self-reacting antibodies in addition to an impairment of platelet production.
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ITP is an autoimmune disease which results in low bloodplateletcounts.