Conclusions: Patients with DM1 can develop rapid changes in cardiacconduction intervals.
2
We hypothesized that overexpression of Cav-3 may alter baseline cardiacconduction and metabolism.
3
Mutations in Cav-3 are implicated in cardiacconduction abnormalities and myopathies.
4
These advances have also improved the ability to detect drug-induced changes in cardiacconduction.
5
This mechanism may underlie some defects in cardiacconduction.
6
Aims: Transgenic mice are frequently used to investigate the role of genes involved in cardiacconduction.
7
Here, we report the effects of constitutive activation of alpha1-adrenergic signaling on connexin phosphorylation and cardiacconduction.
8
The presence of multiple connexins in human ventricle may contribute to divergent mechanisms of regulation of cardiacconduction.
9
Correspondingly, cardiacconduction alterations were especially pronounced in PAmut-infected mice, associated with high mortality rates, compared with PB2mut-infected animals.
10
Functional studies demonstrated that PKC inhibition ameliorated the cardiacconduction defects and contraction abnormalities found in this mouse model.
11
The autopsy ruled the cause of death as " cardiacconduction system abnormality complicated by dehydration during police restraint".
12
Specialized myocytes of the cardiacconduction system (CCS) are essential to coordinate sequential contraction of cardiac atria and ventricles.
13
Molecular pathways involving the homeodomain transcription factor Shox2 control the development and function of the cardiacconduction system in mouse and zebrafish.
14
The alpha 2-and alpha 3-isoform mRNAs are expressed at high levels in the normal adult rat cardiacconduction system.
15
In conclusion, the transcatheter patch might be superior in terms of cardiacconduction system protection in patients with Down syndrome after ventricular septal defect closure.
16
Caveolin-3 (Cav-3) plays a critical role in organizing signaling molecules and ion channels involved in cardiacconduction and metabolism.