MicroRNAs regulate various processes associated with cellsenescence; differentiation, replication and apoptosis.
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Stem cellsenescence is considered deleterious because it may impair tissue renewal and function.
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Therapeutics that induce cancer cellsenescence can block cell proliferation and promote immune rejection.
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Genes and molecules which control either cell proliferation, apoptosis, or cellsenescence have been implicated.
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Renal allograft survival is related directly to cellsenescence.
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To establish the link between p16 and cellsenescence, we stained for Senescence-Associated beta-galactosidase activity.
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This improvement was associated with attenuated β cellsenescence.
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We postulate that fetal cellsenescence signals generated by OS damage are likely triggers for labor.
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The telomeric DNA component shortens each time a somatic cell replicates, eventually leading to cellsenescence.
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Some genes and proteins related to cellsenescence and death are the key factors for pollen abortion.
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Basically anything that supports cellsenescence.
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The resultant disrupted lamin function is highly associated with abnormal nuclear architecture, cellsenescence, apoptosis, and unstable genome integrity.
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The venom significantly induced cellsenescence and repressed cell proliferation and migration in both HaCaT cells and fibroblast cells.
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On the contrary, gain-of-function of CPT1C reversed PANC-1 cellsenescence and enhanced mitochondrial function.
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We performed IT in diet-induced obese rats to investigate the effect of IT on glucose metabolism and β cellsenescence.
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OS damage affects all major cellular elements in the fetal cells , and this damage promotes fetal cellsenescence (aging).