We are using cookies This website uses cookies in order to offer you the most relevant information. By browsing this website, you accept these cookies.
The ID2 protein supports cancer hallmarks including the cancer stem cellstate.
2
Therefore, it allows for a continuous investigation of the cellstate during stretching experiments.
3
Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cellstate.
4
Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cellstate remains fragmentary.
5
These findings demonstrate that somatic cellstate influences requirements for reprogramming and delineate two phases in the process.
6
These results suggest that microtubule dynamics possibly regulates ET(B) receptor expression in astrocytes without affecting the cellstate.
7
Delineating the molecular factors that define and maintain the mammary stem cellstate is vital for understanding normal development and tumourigenesis.
8
Our work reveals how the PLT gradient can regulate cellstate by region-specific induction of cell proliferation genes and repression of differentiation.
9
Organ formation in animals and plants relies on precise control of cellstate transitions to turn stem cell daughters into fully differentiated cells.
10
Single- cell genomics and proteomics enable not only precise characterization of cellstate, but also provide a stunningly high-resolution view of transitions between states.
11
Pluripotency is increasingly recognized as a spectrum of cellstates defined by their growth conditions.
12
Future studies should reveal the molecular basis for the differences in activities between the different cellstates.
13
Such large distributions complicate the statistical evaluation of pharmacological treatments and the comparison of different cellstates.
14
Our work highlights the superior power of proteome profiles to study protein complexes and their variants across cellstates.
15
Second, we define quantitative measures of dynamical modularity, namely that global cellstates are discrete combinations of switch-level phenotypes.
16
Cells were taken from another part of the body, induced into a stem cellstate, and then placed around damaged heart muscle.