Significados de cholesteryl ester em inglês

The mechanism of cholesteryl ester accumulation in smooth muscle cells was investigated.

When membrane cholesterol levels are low, absorption of cholesterol effectively drives cholesteryl ester hydrolysis.

This difference is consistent with reports of the nonendocytotic selective uptake of HDL-associated cholesteryl ester.

Unexpectedly, cholesteryl ester transfer protein was not required to determine the human-like cholesterol lipoprotein profile.

Our results demonstrate that lysosomal hydrolysis of cholesteryl ester is independent of the presence of extracellular acceptors.

We show that net hydrolysis of cholesteryl ester is coupled to the transfer of cholesterol to membranes.

These results show that aortic smooth muscle cells in cooperation with macrophages can accumulate cholesteryl ester from beta-VLDL.

In endosomes and lysosomes cholesteryl ester is hydrolyzed by acidic cholesteryl ester hydrolase producing cholesterol and fatty acids.

Here, we have studied endosomal and lysosomal cholesteryl ester metabolism in cultured mouse macrophages and with cell-free extracts.

J774 and elicited mouse peritoneal macrophages were loaded with cholesteryl ester within lysosomes through phagocytosis of sonicated lipid droplets.

Human plasma lipid transfer protein ( cholesteryl ester transfer protein) has been characterized for its solution and surface properties.

The formation of cholesterol monohydrate crystals was observed in cholesteryl ester-loaded macrophages after a 48-h incubation by polarizing light microscopy.

A reduction in cholesteryl ester transfer protein (CETP) activity has been advanced to explain most lipid-modulating effects of NA.

Additional Mendelian randomization analysis failed to clarify the involvement of cholesteryl ester transfer protein in alcohol-related changes in lipoprotein cholesterol levels.

Electron microscopy and acid phosphatase cytochemistry of lysosomes in cholesteryl ester-loaded cells confirmed that cholesterol crystal formation occurred within lipid-loaded lysosomes.

Thus, the present data do not rule out the involvement of direct HDL-cell interaction in the selective uptake of HDL cholesteryl ester.