Ainda não temos significados para "concomitant mutations".
1We sought to examine the prognostic value of concomitant mutations in PTC.
2Methods: We investigated 88 PTC for concomitant mutations.
3The concomitant mutations may represent intratumor heterogeneity and could exert a gene dosage effect to promote disease progression.
4Conclusions: Our data show that concomitant mutations are a frequent event in advanced PTC and are associated with poor prognosis.
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