Significados de conformational transitions em inglês

This can capture slow conformational transitions or protein binding and unbinding cycles.

These findings may represent general features for functional conformational transitions within the folded state.

In addition our results suggest that adaptive conformational transitions contribute to the specific testosterone-SHBG complex formation.

The localization of histidines within the hinge regions of E implicates these residues in pH-induced conformational transitions.

Poliovirus infection requires that the particle undergo a series of conformational transitions that lead to cell entry and genome release.

We speculate that E proteins could pivot around the fusion loop-pocket junction, allowing virion conformational transitions while minimizing fusion loop exposure.

As a result, we have seen the first real-time simulation of large conformational transitions, including folding and unfolding of short DNA duplexes.

This work explains a coupled mechanism involving several apparently uncorrelated conformational transitions that has only been partially inferred by earlier experimental or theoretical studies.

Here we show that neuronal NOS activation by calmodulin removes constraints favoring a closed 'input state', increasing occupation of other states and facilitating conformational transitions.

Here we have systematically interrogated and scrutinized these conformational transitions using a panel of antibody probes that share a specific preference for the CD4i conformations.

We use conventional and accelerated molecular dynamics (aMD) simulations to explore the conformational transitions of the GPCR from the active state to the inactive state.

Therefore, we utilized 15 N side-chain labeling of Trp residues and 13 C-methyl labeling of Met residues to study substrate-induced conformational transitions of GTB.

The main findings are as follows: (1) Multiple conformational transitions are observed in most of the trajectories within the ultrafast duration of 10 ps.