The use of consolidative RT was associated with significant benefits in both PFS and OS.

A multidisciplinary approach is needed in this setting due to recent, promising results obtained by consolidative immunotherapy.

Those with responding or stable disease received a third course of ASHAP, followed by consolidative treatment with ABMT.

The role of consolidative radiation therapy (RT) in the setting of R-CHOP chemotherapy is not well reported.

Despite a trial of empirical antibiotics, the chest pain and the extent of consolidative lung lesion on chest radiographs rapidly aggravated.

The encouraging OS after autologous HCT, establishes the safety and feasibility of this consolidative treatment option after initial induction therapy for pPCL.

Duration of response did not differ for who achieved at least PR and then either did or did not undergo consolidative transplant.

Consolidative lesions were frequently observed in older children and were associated with more severe clinical features.

Conclusions: Consolidative RT after CR may benefit patients with initial disease above the diaphragm, whereas below-the-diaphragm disease seems to be well managed by chemotherapy alone.