We have attempted to express the Helicobacter pylori vacuolating cytotoxin in Escherichia coli.
2
Serial stool samples were tested for C. difficile colonization by cytotoxin assay and culture.
3
Experiments with animal models suggest that EAEC strains damage the intestinal mucosa, and a putative cytotoxin has been described.
4
These results indicate that IL-4 cytotoxin combined with gemcitabine may provide effective therapy for the treatment of patients with PDA.
5
Specifically, we provide step-by-step instructions for library design and production, optimization of cytotoxin-based selection assays, genome-scale screening, and data analysis.
1
Targeting cell surface receptors with cytotoxins or immunotoxins provides a unique opportunity for tumor therapy.
2
Her nails have turned brown, she suffers from nausea and diarrhoea, and her immune system has been severely compromised by daily injections of cytotoxins.
3
Two potent cytotoxins, TcdA and TcdB are the prime mediators of the syndrome and rapid neutralisation of these would afford significant benefits in disease management.
4
Cytotoxins, which are highly toxic and used to treat cancer, are contained and then sent overseas.
Uso de cytotoxic agents em inglês
1
A number of cytotoxicagents, alone and in combination, have shown activity.
2
Second and 3rd trimester exposure to cytotoxicagents may predispose to placental underdevelopment.
3
Studies incorporating additional cytotoxicagents demonstrate increased morbidity with little benefit.
4
Background: The search for natural products as potential cytotoxicagents has yielded promising candidates.
5
While chemotherapies with cytotoxicagents have demonstrated initial treatment response, most tumors recur quickly.
6
Antitumor effects were equal or superior to that of several clinically approved cytotoxicagents.
7
In the past, most cancer drugs were cytotoxicagents, designed to kill cancer cells.
8
The activity of other cytotoxicagents in this group of patients remains to be established.
9
The treatment paradigms have long been dominant by cytotoxicagents and posed many therapeutic challenges.
10
However, the effect of the availability of cytotoxicagents on survival has not yet been evaluated.
11
The new molecular therapies should be more effective and have less-severe side effects than cytotoxicagents.
12
Combining cytotoxicagents with opposing effects on peripheral nerves has potential for minimizing neurotoxicity in patients.
13
In cells they act as potent cytotoxicagents.
14
These results suggest that AAAD might be an appropriate target for enzyme-activated cytotoxicagents for carcinoid tumors.
15
Discussion and conclusion: Diagnosis of t-MN should be suspected in patients with a history of receiving cytotoxicagents.
16
Given the underlying immunologic nature of these disorders, they are routinely treated with corticosteriods and various cytotoxicagents.