Targeting cell surface receptors with cytotoxins or immunotoxins provides a unique opportunity for tumor therapy.
2
Her nails have turned brown, she suffers from nausea and diarrhoea, and her immune system has been severely compromised by daily injections of cytotoxins.
3
Two potent cytotoxins, TcdA and TcdB are the prime mediators of the syndrome and rapid neutralisation of these would afford significant benefits in disease management.
4
Cytotoxins, which are highly toxic and used to treat cancer, are contained and then sent overseas.
1
A number of cytotoxicagents, alone and in combination, have shown activity.
2
Second and 3rd trimester exposure to cytotoxicagents may predispose to placental underdevelopment.
3
Studies incorporating additional cytotoxicagents demonstrate increased morbidity with little benefit.
4
Background: The search for natural products as potential cytotoxicagents has yielded promising candidates.
5
While chemotherapies with cytotoxicagents have demonstrated initial treatment response, most tumors recur quickly.
Uso de cytotoxin em inglês
1
We have attempted to express the Helicobacter pylori vacuolating cytotoxin in Escherichia coli.
2
Serial stool samples were tested for C. difficile colonization by cytotoxin assay and culture.
3
Experiments with animal models suggest that EAEC strains damage the intestinal mucosa, and a putative cytotoxin has been described.
4
These results indicate that IL-4 cytotoxin combined with gemcitabine may provide effective therapy for the treatment of patients with PDA.
5
Specifically, we provide step-by-step instructions for library design and production, optimization of cytotoxin-based selection assays, genome-scale screening, and data analysis.
6
Based on these studies, we concluded that NO accelerates antitumor effect of IL-13 cytotoxin on head and neck tumor cells.
7
Biochemical data on one of the orphan pathways suggest a previously unknown member of the rare polytheonamide-type cytotoxin family as its product.
8
It causes a progressive and extensive vacuolation of cells followed by necrosis, after a cytotoxin-induced alteration of membrane trafficking by late endosomes.
9
The data indicate that toxin-neutralizing epitopes are conformational and that potential vaccines based on the cytotoxin may benefit from the use of the intact molecule.
10
The aim of this study was to define the association of vacA genotype with gastric inflammation and injury, in vitro cytotoxin activity, and peptic ulceration.
11
Targeting cell surface receptors with cytotoxins or immunotoxins provides a unique opportunity for tumor therapy.
12
Cytotoxins, which are highly toxic and used to treat cancer, are contained and then sent overseas.
13
The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer.
14
Cytotoxin I inhibited the incorporation of phosphate into the 12 and 97 kD polypeptides in a dose-dependent manner.
15
Her nails have turned brown, she suffers from nausea and diarrhoea, and her immune system has been severely compromised by daily injections of cytotoxins.
16
Two potent cytotoxins, TcdA and TcdB are the prime mediators of the syndrome and rapid neutralisation of these would afford significant benefits in disease management.