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In this case, magnetic resonance imaging was useful in diagnosing dedifferentiated chondrosarcoma before surgery.
2
Fifty cases were retrieved, reviewed and FNCLCC grade was scored for the dedifferentiated component.
3
T2-weighted imaging was used to distinguish between the cartilaginous component and the dedifferentiated one.
4
Epithelial glandular differentiation in dedifferentiated chondrosarcoma has not been described.
5
However, the molecular identity of the differentiated and dedifferentiated states in vivo has been elusive.
6
In vitro dedifferentiated plant cell cultures are a useful tool for the study of molecular processes.
7
We conclude that ERalpha activation switched SMC to a dedifferentiated phenotype and may contribute to plaque instability.
8
Immunohistochemical staining revealed strong expression of vascular endothelial growth factor in the tumor cells in the dedifferentiated component.
9
In well-differentiated and dedifferentiated liposarcoma their clinical promise is associated with their ability to downregulate the MDM2 protein.
10
Although the tumors are usually indolent in their growth, the more dedifferentiated or anaplastic tumors can be quite aggressive.
11
Both peripheral and central dedifferentiated chondrosarcomas are high-grade malignant lesions and require wide or radical surgical margins for adequate treatment.
12
MDM2 amplification level remains a useful diagnostic tool in dedifferentiated liposarcoma, but has no prognostic value in terms of local recurrence.
13
We present a case of dedifferentiated liposarcoma arising in the pyriform sinus, an event only twice reported previously in the literature.
14
In transcription factor-induced molecular reprogramming, Nanog is initially dispensable but becomes essential for dedifferentiated intermediates to transit to ground state pluripotency.
15
The aim of this study was to get more insight into the molecular characteristics of dedifferentiated carcinomas using high throughput techniques.
16
The absence of alphaSMA-positive cells in regions of RPE atrophy suggests that RPE are lost rather than persist in a dedifferentiated state.