1
The structures of these dendrimers are established by spectroscopic and analytical techniques.
2
This review will also investigates the benefits utilizing dendrimers for cancer diagnosis and therapy.
3
The aggregation caused by large cationic dendrimers was proportional to the number of surface amines.
4
Mitsunobu reactions were utilized to provide high-yielding steps allowing large-scale production of the novel dendrimers.
5
Here we report evaluation of 12 formulations of PAMAM dendrimers varying in size and surface charge.
6
Employed in imaging diagnostics, dendrimers reduce the dosage required to obtain images, thus improving the efficiency of radioisotopes.
7
The rapid clearance of systemically administered dendrimers from major organs promises minimal off-target adverse effects of conjugated drugs.
8
We show that the FA modification renders the dendrimers with targeting specificity to cancer cells overexpressing FR in vitro.
9
The aim of this study is to evaluate the appearance of HIV-1 resistance mutations after treatment with polyanionic carbosilane dendrimers.
10
These materials are prepared by sequestering metal ions within dendrimers followed by chemical reduction to yield the corresponding zerovalent metal nanoparticle.
11
Because of these features researchers are particularly excited about the potential application of dendrimers as a versatile carrier for drug delivery.
12
Taken in context with previously reported studies, our data suggest that large cationic PAMAM dendrimers induce platelet aggregation through disruption of membrane integrity.
13
The experimental results indicate that polygalloyl dendrimers might be used as new lead compounds to improve the long-term healing characteristics of burn wounds.
14
The catalytic rate constant kcat depended on the placement of histidines within the dendrimers and the nature of the other amino acid residues.
15
The synthesis of a novel and attractive class of nonsteroidal anti-inflammatory and antimicrobial organoiron dendrimers attached to the well-known drug ibuprofen is achieved.
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He's located just 100 miles south of a nanotech pioneer: former Dow chemist Donald Tomalia, who had invented a type of particle called dendrimers.