Significados de emodepside em inglês

It increases activation of SLO-1 K+ currents and potentiates effects of emodepside.

The efficacy of emodepside was determined by faecal egg counts.

The effect of emodepside was reduced in Ca-free solutions.

The effect of emodepside was enhanced by stimulation of protein kinase C and NO pathways.

Our observations show that emodepside has potent macrofilaricidal effects and alternative splicing in the RCK1 binding pocket affects potency.

Our results suggest consideration of the combination of emodepside and diethylcarbamazine for therapy, which is predicted to be synergistic.

In this paper we comment on some recent observations of ours on the modes of action of emodepside, diethylcarbamazine and tribendimidine.

The untreated mothers of the latter stayed also coproscopically negative, which might be explained by an oral uptake of emodepside through grooming.

The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics.

However, direct effects of emodepside on Slo-1 have not been reported and these channels have only been characterized for C. elegans and related Strongylida.

In silico modeling identified an emodepside binding pocket in the same RCK1 region of different species of filaria that is affected by these splice variations.

Emodepside is a resistance-busting anthelmintic approved for treating intestinal parasitic nematodes in animals.

Emodepside had no effect on voltage-activated Ca currents.

Emodepside, a veterinary anthelmintic registered for treatment of nematode infections in cats and dogs, is reported to have macrofilaricidal effects.

It increases activation of SLO-1 K+ currents and potentiates effects of emodepside.

The efficacy of emodepside was determined by faecal egg counts.