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Human endogenousretroviruses (HERVs) comprise a significant portion of the human genome.
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And that process in mice, at least, is also under the influence of endogenousretroviruses.
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So that viral DNA got passed down from generation to human generation as so-called endogenousretroviruses.
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Human endogenousretroviruses (HERVs) arose in antiquity from stable integration into the human genome.
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In some animal models of autoimmune diseases the roles of exogenous and endogenousretroviruses are clearly defined.
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Porcine endogenousretroviruses (PERV) are of concern when the microbiological safety aspects of xenotransplantation are considered.
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We find that the repression of specific murine endogenousretroviruses is dependent on DAXX, but not on ATRX.
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The question now is whether the role of endogenousretroviruses in the immune system is similarly widespread among animals.
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Our analysis provides informations on dUTPase phylogeny and further shows that endogenousretroviruses provide important informations regarding retrovirus evolution.
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Human endogenousretroviruses (hERVs) are remnants of exogenous retroviruses that have integrated into the genome throughout evolution.
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The potential transmission of porcine endogenousretroviruses (PERVs) has raised concern in the development of porcine xenotransplantation products.
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Thus, cORF of human endogenousretroviruses may contribute to tumor development by interfering with processes during spermatogenesis that involve PLZF.
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The coding capacity for retroviral Gag and Env proteins has been maintained in human endogenousretroviruses of the HERV-K family.
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The human genome contains a significant amount of human endogenousretroviruses (HERV) representing fossilized sequences of ancient exogenous retroviruses.
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And in recent years, scientists poring over gigabytes of genetic sequencing data have seen other tantalizing hints of endogenousretroviruses turning useful.
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Background: The risk of zoonotic infection by porcine endogenousretroviruses (PERV) has been highlighted in the context of pig-to-human xenotransplantation.