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Significados de genomic instability em inglês

russo
геномная нестабильность
espanhol
inestabilidad genómica

Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage.

геномная нестабильность
Uso de genomic instability em inglês
1
Cells from patients with genomic instability syndromes have high predisposition to cancer.
Pubmed
2
Deregulated activation of β-catenin in cancer has been correlated with genomic instability.
Pubmed
3
Moreover, the different patterns of alteration imply distinct underlying mechanisms of genomic instability.
Pubmed
4
NOS-induced ROS release leads to DNA damage and genomic instability in DMD hPSC.
Pubmed
5
Although R-loops are normal transcriptional intermediates, they are also associated with genomic instability.
Pubmed
6
Actively transcribed regions of the genome are vulnerable to genomic instability.
Pubmed
7
Rare cells escaping senescence by restoring SKP2 expression display genomic instability.
Pubmed
8
The mechanisms contributing to transcription-associated genomic instability are both complex and incompletely understood.
Pubmed
9
Chromosomal destabilization is one end point of the more general phenomenon of genomic instability.
Pubmed
10
Whether Polθ interacts with canonical DNA repair pathways to prevent genomic instability remains unknown.
Pubmed
11
Such coincidences may result in collisions that trigger genomic instability.
Pubmed
12
The genomic instability, adaptive response formation, genome damage and oxidative status have been investigated.
Pubmed
13
Therefore, persistently increased oxidative stress has been proposed as a mechanism for UV-induced genomic instability.
Pubmed
14
Mechanisms underlying genomic instability in MM are largely unknown.
Pubmed
15
If not properly repaired, these lesions can lead to mutations, genomic instability, and cell death.
Pubmed
16
Nevertheless, several studies indicate that AML cells show high levels of DNA lesions and genomic instability.
Pubmed
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Translations for genomic instability
Genomic instability ao longo do tempo
Genomic instability nas variantes da língua
Estados Unidos da América
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