Significados de genomic stability em inglês

Furthermore, the general role of NHEJ in promoting genomic stability will be discussed.

The tumor suppressor protein p53 plays a major role in preserving genomic stability.

Cell-cycle checkpoints are signal-transduction pathways required to maintain genomic stability in dividing cells.

We conclude that MSH6 protects B cells from neoplastic transformation by preserving genomic stability.

Magnesium maintains genomic stability and is an essential cofactor for DNA synthesis and repair.

Chk1 is essential in maintaining genomic stability due to its role in cell cycle regulation.

In this review, we discuss the critical roles that hSSB1 plays in the maintenance of genomic stability.

These data suggest that high-fidelity DNA synthesis by DNA polymerase alpha is required for genomic stability in yeast.

Repair of DNA double-strand breaks is critical to genomic stability and the prevention of developmental disorders and cancer.

Thus, cellular levels of CHK1 likely play a key role in the maintenance of genomic stability and preventing tumorigenesis.

Therefore, we infer that DYNLL1 is an important anti-resection factor that influences genomic stability and responses to DNA-damaging chemotherapy.

These ligase-generated 5'-adenylylated nicks constitute persistent breaks that are a threat to genomic stability if they are not repaired.

Additionally, Cdh1 tends to play an important role in maintenance of genomic stability, the detailed mechanisms deserve further study.

Maintenance of genomic stability is essential for normal organismal development and is vital to prevent diseases such as cancer.

Furthermore, we used this assay to determine the effects of BRCA1 variants on cell cycle regulation, differentiation, and genomic stability.

Mutations in LMNA result in altered nuclear morphology, but how this impacts the mechanisms that maintain genomic stability is unclear.