Significados de germinal center em inglês

Further analyses revealed a germinal center B-cell-like phenotype of most BATF3-initiated lymphomas.

A germinal center B-cell-like profile was frequently associated with SV40-positive lymphomas.

In reactive tonsils, Skp2 expression was limited to proliferating germinal center and interfollicular cells.

This would indicate that these epitopes are selectively recognized and presented to germinal center B-cells.

Staining of the follicular dendritic cell revealed its meshwork structure limited in the germinal center.

Despite the abnormal Ab response, germinal center formation was retained in all of the chimeric animals.

Tumors originate in mesenteric lymph nodes and in Peyer's patches and resemble human germinal center lymphomas.

Seven of eight patients with double hit lymphoma had the germinal center subtype with poor outcome.

Expression of PAG may reflect its role in regulation of proliferation and differentiation of germinal center B-cells.

BCL-6 somatic mutations have been described in normal and tumoral B lymphocytes, associated with germinal center transit.

GL7 expression has also been demonstrated on thymocytes, germinal center B cells and some neuronal cell types.

Tcf4-haplodeficient SLE-prone animals showed a reduction of the spontaneous germinal center reaction and its associated gene expression signature.

Thus, this novel receptor has the potential to function in carbohydrate-mediated communication between cells in the germinal center.

There, they are activated by antigen-specific T cells and become germinal center (GC) founder B cells.

In lymph nodes, germinal center formation was examined and numbers of proliferating cells were evaluated by Ki-67 staining.

Notably, bortezomib treatment induced germinal center B cell and follicular helper T cell expansion in the lymph nodes.