Chemotherapy should not be employed in the initial management of hairy cell leukemia.

Two patients with hairy cell leukemia treated with the anthracycline antibiotic rubidazone are presented.

Tumor cells of hairy cell leukemia are mostly AID.

A provisional diagnosis of hairy cell leukemia was made.

Splenectomy is also offered in selected cases of leukemia and lymphoma but is going out of practice for hairy cell leukemia and Hodgkin's disease.

Immunotoxins have produced many durable complete responses in refractory hairy cell leukemia, where patients rarely form antibodies to the bacterial toxin component of the immunotoxin.

Reports indicate that when these two MoAbs co-express, they represent a unique marker for hairy cell leukemia (HCL) although neither is specific for that disease.