Background & aims: Recurrence of hepatocellularcancer after resection is a significant problem.
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HCV infects millions of people worldwide and is a leading cause of liver cirrhosis and hepatocellularcancer.
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Conclusions: Second hepatic resection for recurrent hepatocellularcancer is applicable in about 15% of patient with recurrence.
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We analyzed the outcomes of patients undergoing a second hepatic resection for recurrent hepatocellularcancer at a single Western center.
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We previously showed that for hepatocellularcancer (HCC) prognostication, disease parameters need to be considered within a total personal clinical context.
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Loss of β2-spectrin leads to defects in liver development, and its haploinsufficiency spontaneously leads to chronic liver disease and the eventual development of hepatocellularcancer.
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Methods: The records of all patients undergoing primary hepatic resection for hepatocellularcancer between January 1994 and January 2009 were reviewed.
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Conclusion: Tumor-specific proteomic signatures may be useful for detection and classification of hepatocellularcancers.