Medical agency in Dublin, Ireland, subsidiary of the public health service (Health Service Executive)
1The results may lead to mass production of hPSC-VCMs in bioreactors.
2Furthermore, the HPSC has been notified of six more confirmed cases of Covid-19.
3NOS-induced ROS release leads to DNA damage and genomic instability in DMD hPSC.
4This hampers the study of hPSC-generated astrocytes in disease processes and drug development.
5Here we dissect the cellular and molecular implications of this trisomy in hPSCs.
6This in turn improves metabolic and functional maturation of hPSC-CMs.
7Little is known about the underlying signaling pathways controlling hPSC-CMs' metabolic and functional maturation.
8We hypothesized that fatty acid supplementation would enhance hPSC-CM maturation.
9The patient achieved a complete and uncomplicated engraftment following each cycle of HPSC-supported high-dose therapy.
10Chemokines mediate both differentiated and undifferentiated states of hPSCs.
11Here we address this open question by investigating the regulation of hPSC neurogenesis by microenvironmental stiffness.
12However, the basic mechanisms required for proliferation and self-renewal of hPSCs have not been fully uncovered.
13These hPSC lines can be used to study the role of DLL4 during human embryonic development.
14The HPSC group will produce national recommendations for laboratory diagnosis, surveillance and management of C. difficile infection.
15Here, we investigate how hPSCs tightly control their energy homeostasis by studying the main energy-consuming process, mRNA translation.
16Together, these findings demonstrate the extensive effect of trisomy 12 and highlight its perils for successful hPSC applications.