Significados de human leukemia em inglês

OSI-211 has significant activity in severe combined immunodeficient mouse models of human leukemia.

Aberrations in the AML1 gene are frequently found in human leukemia.

Apaf-1 deficiency may constitute a significant mode of resistance to apoptosis in human leukemia.

This finding may reveal a key role for EAP30 in the pathogenesis of human leukemia.

Several genetic aberrations that disrupt the function of AML1 have been frequently observed in human leukemia.

Moreover, mutant MOLT-4, human leukemia cells lacking functional mitochondria, were found to be resistant to Aplidin.

Interestingly, this protection was independent of cell-cell contact, and it extended to human leukemia cell lines as well.

We have previously demonstrated that oHA can revert Vincristine resistance in mouse lymphoma and human leukemia cell lines.

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia occurring as indolent or aggressive form.

The results described here further demonstrate that the HLA-G molecule is not expressed in freshly isolated human leukemia cells.

It exerted a potent antitumor effect toward human leukemia cells through the induction of apoptosis via an intrinsic pathway.

The anti-proliferative activity of these agents against human leukemia and various solid tumor cell growth in vitro was studied.

We found that the drugs in combination had cytotoxic synergism against human leukemia cell lines (K-562 and Raji).

Moreover, when we tested fresh human leukemia progenitor cells, amifostine pretreatment sensitized the leukemic cells to the cytotoxic effects of NM.

Moreover, similar enhancement of TM by these agents was also observed in another human leukemia cell line, HEL, which has megakaryocytic markers.

In this study, we identified an insoluble protein that was associated with the chromatin-depleted nuclear structure of proliferating human leukemia HL-60 cells.