Regulators of the immune system.
1Conclusion: Current data from clinical trials with immune checkpoint modulators are promising.
2Conclusions: HLH is a rare but serious complication of immune checkpoint blockade.
3Response to immune checkpoint inhibitors correlates with a pre-existing anti-tumoral immune response.
4Tumor associated inflammation predicts response to immune checkpoint blockade in human melanoma.
5Adenosine with its strong immunosuppressive properties is an important immune checkpoint molecule.
6Variant urothelial carcinoma should not exclude patients from receiving immune checkpoint inhibitors.
7Blockade of IL-17 signaling resulted in increased expression of immune checkpoint markers.
8Conclusions: Overall response rate to immune checkpoint inhibitors was comparable across histological types.
9However, little evidence supports the efficacy of immune checkpoint inhibitors as neoadjuvant chemotherapy.
10Coexpression analysis indicated that CD3D is correlated with immune checkpoint and immune-infiltrated cells.
11A significant proportion of cancer patients do not respond to immune checkpoint blockade.
12Conclusions: IFN-γ is an important marker for prediction of response to immune checkpoint blockade.
13Background: Chemotherapy may exert immunomodulatory effects, thereby combining favorably with the immune checkpoint blockade.
14TIL isolated from tumor bearing mice were tumor-specific and expressed co-inhibitory immune checkpoint molecules.
15Background: In recent years, new immunotherapeutic drugs have become available: the so-called immune checkpoint modulators.
16Background and purpose: Hypophysitis is one of the well-known adverse effects of immune checkpoint inhibitors.
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Immune checkpoint nas variantes da língua
Estados Unidos da América