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Meanings of invalidate comparison in inglês

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Usage of invalidate comparison in inglês
1
Statistical analyses were not performed because patients with radiation only had more advanced disease, invalidating comparison.
Pubmed
2
In recent years these have added tens of thousands of additional beneficiaries, thus invalidating comparisons between different periods.
The Irish Times
3
This does not really invalidate comparisons between different areas so seriously as we might at the first glance be tempted to expect.
Missionary Survey As An Aid To Intelligent Co-Operation In Forei...