In conclusion, our study provides a clear motivation for including chrX in large-scale genetic studies of complex diseases and traits.

The CHR is the main UN forum for discussing human rights issues.

CHR subjects did not differ from patients in terms of premorbid functioning.

All adult CHR residents with PLA were identified, and charts were reviewed.

The present study includes participants from the FFT-CHR sub-study and non-randomized NAPLS2 participants.