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The findings suggest gender-specific alterations of hemispheric lateralisation in schizophrenia.
2
Functional lateralisation is a fundamental principle of the human brain.
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However, a comprehensive taxonomy of functional lateralisation and its organisation in the brain is missing.
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Handedness did not influence symptom lateralisation.
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The results indicate that an atypical cerebral lateralisation underlying non-right-handedness may be also a contributing factor to positive schizotypy.
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In this magnetoencephalography study the issue of hemispheric lateralisation in patients with schizophrenia was addressed using acoustically evoked neuromagnetic fields.
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This supports the notion that reduced manual lateralisation in schizophrenia is related to the illness rather than to familial left-handedness.
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This latter result suggests that during evolution, brain size expansion led to functional lateralisation to avoid excessive conduction delays between the hemispheres.
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Therefore the aim of this study was to investigate the strength of manual lateralisation in patients with first episode schizophrenia, taking into account familial sinistrality.