Meanings of major locus in inglês

These results suggest that APOB is not the major locus influencing plasma apoB levels.

These concordant findings in mice and humans implicate HTR2B as a major locus associated with cannabis-induced aggression.

Some mixed genetic models support single major locus inheritance, but transmission probabilities do not conform to Mendelian expectations.

The results suggest that the susceptibility for TS is conveyed by a major locus in combination with a multifactorial background.

A definitive replicable genetic linkage for a major locus underlying the susceptibility to schizophrenia has not been identified to date.

In each sample, the model incorporated a major locus pleiotropic effect, and residual correlation was found to be the most parsimonious model.

A large and remarkable family is described in which febrile convulsions appear to result from autosomal dominant inheritance at a single major locus.

Other models of inheritance were definitively rejected, including strictly polygenic models, all single major locus models, and mixed models with dominant and recessive major loci.

Lod scores were positive in all four families, suggesting that chromosome 7q21-q31 is a major locus for myoclonus-dystonia with several phenotypes.

The major locus accounts for over half of the phenotypic variance for TS, whereas the multifactorial background accounts for approximately 40% of phenotypic variance.

Both parental strains carry the pulmonary adenoma susceptibility 1 (Pas1) locus, a major locus affecting predisposition to lung cancer in mice.