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Conservation of flanking genes in mammalianevolution indicates maintenance of synteny.
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This article illustrates the power of this resource for exploring vertebrate and mammalianevolution, using three examples.
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CD1 proteins have been conserved throughout mammalianevolution and function to present lipid antigens to T cells.
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This may indicate a trend of having fewer larger islets comprising several endocrine cell types during mammalianevolution.
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Background: Transposed elements (TEs) have a substantial impact on mammalianevolution and are involved in numerous genetic diseases.
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It also allows us to speculate about the events that led to tissue-specific regulation of the Pgk2 gene during mammalianevolution.
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The emergence of this thermogenic organ during mammalianevolution remained unknown as the identification of UCP1 in marsupials failed so far.
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The neocortex represents the brain region that has undergone a major increase in its relative size during the course of mammalianevolution.
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Differences were discovered between mammoth and African elephant in amino-acid positions that are otherwise invariant over several billion years of combined mammalianevolution.
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The availability of large TF combinatorial networks in both human and mouse will provide many opportunities to study gene regulation, tissue differentiation, and mammalianevolution.
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If dinosaurs had somehow been able to keep their claw grip on the global ecology, they would have undoubtedly continued to influence mammalianevolution, too.