Photofrin- mediatedPDT combined with either celecoxib or NS-398 increased cytotoxicity and apoptosis in mouse BA mammary carcinoma cells.
5
Methods: Mouse mammary carcinoma (BA) cells and transplanted BA tumors growing in C3H mice were treated with PH- mediatedPDT.
6
A model of bone metastasis in rat confirmed the efficacy of benzoporphyrin derivative-monoacid- mediatedPDT for treating lesions within the spine and appendicular bone.