Clinical manifestations included moderatementalretardation, destructive behavior, and minor physical anomalies.
2
Results: The clinical picture was characterized by bilateral congenital cataract, developmental delay, and slowly progressive neurological impairment with spasticity, cerebellar ataxia, and mild-to- moderatementalretardation.
3
Macrocytic anemia was present in 8 cases and sub-clinical hypothyroidism in 5 cases, and mild to moderatementalretardation in 4 cases.
4
Well, in Fragile X, the consequence is-orwas, before we learned to repair it- moderatemental retardation.