Etiology is thought to involve complex, multigenic interactions and possible environmental contributions.
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Taken together, these results indicate that MeLiM swine is a model for human multigenic diseases.
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Here, we present sequencing data of a family with a potentially multigenic origin of CHD.
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Background: Psychiatric disorders are multigenic diseases with complex etiology that contribute significantly to human morbidity and mortality.
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Although poorly understood, it has long been recognized that host regulation of virus-associated disease severity is multigenic.
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The mode of inheritance remains to be determined, but it appears to be complex and potentially multigenic.
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Hypertension is a multigenic disorder in which abnormal counterregulation between dopamine and Ang II plays a role.
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Moreover, our study highlights the need for new approaches allowing a multigenic analysis to clarify the genotype-phenotype correlation in TRB.
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They probably constitute the entire chs multigenic family of this fungus, as revealed by careful analysis of six euascomycetes genomes.
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The mandibles of F(1) hybrids are mostly intermediate between parental phenotypes as expected for a complex multigenic character.
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Thirteen single-copy genes were used for phylogenetic analysis; the resulting trees are largely consistent with those inferred from multigenic plastid datasets.
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Unlike other diseases, such as cystic fibrosis, that are caused by defects in one specific gene, asthma is a so-called multigenic disease.
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Acquisition of a metastatic phenotype by breast cancer cells includes alternations of multigenic programs that permit tumor cells to metastasize to distant organs.
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Highly transcribed genes were present in multigenic salt-soluble chromatin domains ranging in length from 30 to over 150 kb.
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It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria of the gut.
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These results indicate that resistance to DX and MTX in human OS cell lines is a multigenic process involving gene copy number and expression changes.