Significados de mutational heterogeneity em inglês

Clinical variability of the XP-A phenotype is associated with a mutational heterogeneity.

Single cell analyses revealed mutational heterogeneity among CTCs and tumor cells in tissues.

Twenty-six novel variants were reported from both genes, and BRCA2 showed higher mutational heterogeneity.

Despite a relatively homogenous mutational spectrum, mutational heterogeneity for rare cases is observed because of the high rate of consanguinity.

Identification of novel causing mutations in Tunisian XP-A patients shows the genetic and mutational heterogeneity of the disease in Tunisia.

However, information is limited regarding mutational heterogeneity among CTCs and metastases in breast cancer as discerned by single cell analysis.

Acute myeloid leukemia (AML) remains difficult to treat due to mutational heterogeneity and the development of resistance to therapy.

The report provides additional evidence in support of the rich variability in phenotypic expression, the mutational heterogeneity and ethnic diversity associated with this rare condition.

We herein formulate the hypothesis that high levels of mutational heterogeneity in the tumor could be the key for the success of immune checkpoint-targeting therapies.

Mutational heterogeneity of breast cancer suggests that about a dozen of cancer genes consistently mutate, together with many other genes mutating occasionally, in patients.