Significados de normal allele em inglês

Clinically normal parents of XP-C patients have one mutant allele and one normal allele.

Four carrier females showed the mutant as well as the normal allele; none showed clinical features of Kennedy's disease.

These observations suggest that this mosaic pattern might have resulted from somatic reversion of the mutated allele to the normal allele in blood-forming cells.

The original tumor DNA did not hybridize with the oligonucleotide representing the mutated allele, but did hybridize with the one representing the normal allele.

No mutation was found in the COL4A5 promoter region by sequencing nor was a major rearrangement of the normal allele detected.

Primary carcinomas were generally characterized by genomic loss of normal alleles of the mutant genes.

Repeats on normal alleles contained from 7 to 35 CAGs.

Normal alleles vary from 6 to 25 copies.

Examination of normal DNA from the same patient demonstrated that both lesions are somatic and associated with loss of both normal alleles.

Normal alleles had 26 to 35 repeats.

The range of normal alleles varied from 17 to 30 CAG repeats and from 35 to 51 repeats for the pathological alleles.

The results show that 64.7% of the Siberian normal alleles contain a single CAT interruption, whereas 92% of the Chinese had more than 1 interruption.