On incubation at 37 degrees C, this activity dissociates from the nucleoskeleton to give a soluble activity that prefers broken templates.
2
Analogues were concentrated in approximately 2,100 (range 2,000-2,700) discrete sites attached to a nucleoskeleton and surrounded by chromatin.
Uso de nuclear matrix em inglês
1
Neither viral DNA nor viral DNA polymerase activity was associated with the nuclearmatrix.
2
Recent studies have documented the presence of tumor-associated nuclearmatrix proteins in several human cancers.
3
The functional significance of the nuclearmatrix association of these transcription factors remains to be determined.
4
Thus, the association of the histone deacetylase with the internal nuclearmatrix is neither tissue- nor species-specific.
5
Carcinogenic property of AML1-MTG16 is restricted to its localization in the nuclearmatrix.
6
Electron microscopic study showed that empty capsids were bound to the filamentous networks of the nuclearmatrix of the late stage.
7
We used high-resolution two-dimensional gel electrophoresis to compare nuclearmatrix protein patterns in cervical carcinomas with those from normal cervical tissue.
8
It is thought that the nuclear nonchromatin structures, such as the nuclearmatrix and lamina, play regulatory roles in gene expression.
9
These results may indicate that the nuclearmatrix plays some role in the growth of herpes simplex virus, especially during the morphogenesis.
10
Association of transcription factors with the nuclearmatrix represents a mechanism by which nuclear architecture may influence transcriptional control of gene expression.
11
The data from these experiments reveal that ubiquitously represented and tissue restricted regulatory proteins are associated with nuclearmatrix of lens epithelial cells.
12
These proteins have a short half-life and are localized to the nuclearmatrix fraction, as previously reported for the c-myc and N-myc proteins.
13
However, they do co-localize with non-A, the human orthologs of which are implicated in both RNA splicing and attachment of dsRNA to the nuclearmatrix.
14
The protein composition of the nuclearmatrix changes significantly as the osteoblast matures from a proliferating pre-osteoblast to an osteocyte embedded in a mineralized matrix.
15
Annealing studies were performed on DNA fragments associated with rat and mouse liver interphase nuclearmatrix and the metaphase scaffold of Chinese hamster DON cells.
16
Taken together, our results suggest that developmental association of galectin-1 with the nuclearmatrix reflects differential subnuclear binding of galectin-1 during osteoblast differentiation.