Using nanotechnology, we created a mouse model of corticosteroid-induced ocularhypertension.
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The main complications after surgery were hyphema, ocularhypertension, and moderate anterior chamber reaction.
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Thus, PhXA41 was well tolerated in subjects with ocularhypertension or primary open-angle glaucoma.
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The new drug was tested on patients with primary open-angle glaucoma and ocularhypertension.
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These results suggest LIMK2 may be an effective target for treating ocularhypertension and associated glaucoma.
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The cause of the elevated outflow resistance and consequent ocularhypertension characteristic of glaucoma is unknown.
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Methods: This was a double-masked, randomised, parallel comparison study in patients with open-angle glaucoma or ocularhypertension.
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Participants: We evaluated 52 eyes of 30 patients with glaucoma or ocularhypertension.
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Purpose: To describe the risk and risk factors for ocularhypertension (OHT) in adults with noninfectious uveitis.
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Conclusions: The costs of patients with glaucoma were twice as high as the costs of patients with ocularhypertension.
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Overexpression also increased survival of cells subjected to oxidative stress linked to ocularhypertension, associated with TP53 pathway activation.
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Background: Several ocular side effects including uveitis, have been reported following topical beta blocker treatment for glaucoma and ocularhypertension.
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These results support the option of SLT as a safe and effective initial therapy in open-angle glaucoma or ocularhypertension.
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Patients and methods: Sixty-nine patients (127 eyes) with open-angle glaucoma or ocularhypertension were randomized to SLT or medical therapy.
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The authors concluded that bimatoprost is an effective, well-tolerated treatment for lowering intraocular pressure in Thai patients with open-angle glaucoma or ocularhypertension.
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After topical dosing to the eye in a steroid induced mouse model of ocularhypertension, the compounds reduce intraocular pressure to baseline levels.