We have isolated and characterized a novel human and rat organicanion transporter subtype, OATP-D.
2
The effect of probenecid, an inhibitor of organicanion transport, on these measurements was also investigated.
3
Human organicanion transporter hOAT1 plays a critical role in the body disposition of clinically important drugs.
4
Future studies are needed to determine whether these metabolites can serve as qualified biomarkers for organicanion transporters.
5
Phylogenetic tree analysis revealed that OATP-D is branched in a different position from all known organicanion transporters.
6
Human organicanion transporter hOAT1 plays critical roles in the body disposition of environmental toxins and clinically important drugs.
7
The cloning of the gene for cmoat opens up new possibilities to study the regulation of hepatic organicanion transport.
8
It is suggested that HvALMT1 functions as an anion channel to facilitate organicanion transport in stomatal function and expanding cells.
9
This study's purpose was to determine NBCe1's role in a third component of acid-base homeostasis, organicanion metabolism, by studying mice with NBCe1 deletion.
10
NMR analyses showed no generalized increase in urinary excretion of organicanions.
11
Organicanion concentration in these plants was much higher in the shoots than in the roots.
12
Organicanion salts that are found primarily in plant foods are directly absorbed in the gastrointestinal tract and yield bicarbonate.
13
A mechanism of Al(3+) tolerance discovered in many plant species involves the release of organicanions from root apices.
14
To investigate the mechanism of sepsis-associated hyperbilirubinemia we have studied hepatocanalicular transport of organicanions in a rat model of endotoxemia.
15
Establishment of hOAT4-expressing BeWo cells provided useful tool for further pharmacological and molecular biological studies of placental transport of organicanions mediated by this carrier.
16
These findings show that biliary transport of organicanions and possibly other canalicular transport is influenced by the entry of hepatocytes into the cell cycle.