The most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known.
Conclusions: TGF-beta promotes development of pancreaticfibrosis after recurrent episodes of acute pancreatitis.
2
Immunostaining with fibronectin antibody was used to quantify the extent of pancreaticfibrosis.
3
Genistein induced the expression of let-7d and might modulate pancreaticfibrosis.
4
Its role in pancreaticfibrosis and neuropathy is unknown.
5
This model of pancreaticfibrosis could be used as a model of chronic pancreatitis consistent with the necrosis-fibrosis sequence hypothesis.
6
Conclusions: Prior surgery is strongly correlated with the extent of pancreaticfibrosis, islet yield, and insulin requirements in CP patients undergoing TP-IAT.
7
The pancreatic renin-angiotensin system plays a role in the development of pancreaticfibrosis and ACE inhibitors decrease pancreaticfibrosis in experimental models.
8
There are currently no drugs limiting pancreaticfibrosis associated with CP, and there is a definite need to fill this void in patient care.
9
Pancreaticfibrosis, islet yield, cell viability, and insulin requirement were measured.