Significados de partial agonist em inglês

However, both mutant subunits enhanced partial agonist efficacies in the LS-biased preparation.

It acts as with partial agonist activities at the dopamine D2 receptors.

Tamoxifen has partial agonist effects with ERalpha but not with ERbeta.

We have previously shown that MG is a competitive partial agonist at GABA-A receptors.

However, the compounds presented here display partial agonist or antagonist behavior instead of full agonist.

The affinity constants for Ado and ATP were identical, although ATP was a partial agonist.

Noradrenaline behaved as a full agonist and St-587 as a partial agonist for this response.

Elevations in serum prolactin following nalmefene are consistent with this partial agonist effect at kappa-opioid receptors.

It has been suggested that tamoxifen mediates its partial agonist activity through AP-1 at target promoters.

Finally, flutamide was observed to be a weak partial agonist of the wild-type AR in this system.

Binding of the partial agonist JMV180 and the antagonist JMV179 were unaffected.

Buprenorphine is a weak partial agonist at mu-opioid receptors that is used for treatment of pain and addiction.

The analog might act as an activator of regulatory T cells or as a partial agonist of TCR.

D-Amino acid substitution was employed to search for novel AII antagonists that would also display reduced partial agonist activity.

Selective receptor modulators, such as the antiprogestin RU486, are known to exhibit partial agonist activities in a cell-type-dependent manner.

Thus, the ability of a partial agonist to interact with these two different domains may be a determinant of efficacy.