A small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication.
1An obvious size change was not observed when plasmid DNA was added.
2Analytical sensitivity was 10 copies of control plasmid DNA per reaction.
3Thus, interrupted plasmid DNA does not accumulate in the absence of DNA replication.
4All studied complexes caused single-stranded cleavage of the sugar-phosphate backbone of plasmid DNA.
5In vivo expression was detected after injection of plasmid DNA into mouse quadriceps.
6It has been a decade since plasmid DNA was first introduced orally in animals.
7Here we used injections of plasmid DNA encoding luciferase to further characterize this mechanism.
8Alternative approaches using rAAV plasmid DNA in nonviral gene delivery systems also generated promising results.
9Directly after retrieval and return transport of the payload, the plasmid DNA samples were recovered.
10Here, we examined the brain targeting efficiency and transport pathways of intranasally administered plasmid DNA.
11Intramuscular plasmid DNA injection results in long-term but low and variable expression of the injected genes.
12A complex of the cationized gelatin and plasmid DNA of BMP-2 was impregnated into the scaffold.
13Naked pCMV-EGFP plasmid DNA did not express the reporter gene to the levels of the adeno-EGFP.
14Processing time, from E. coli culture to usable plasmid DNA, is two minutes or less per sample.
15At the restrictive temperature the plasmid DNA collects as an open circular form with single strand interruptions.
16The infiltration of inflammatory cells into the sites where the IL-6-expressing plasmid DNA was delivered was observed.
Translations for plasmid DNA