Meanings of rational drug design in inglês

I'm a believer in this what you call rational drug design.

A recent trend toward more rational drug design was observed.

The discovery of these agents has not always been the result of rational drug design.

This advanced in silico approach is valuable to achieve rational drug design of selective G4 binders.

Gene silencing by double-stranded RNA, denoted RNA interference, represents a new paradigm for rational drug design.

A rational drug design should take this into account for screening molecules with improved permeation properties.

Recent findings: Within the last year, exome-wide analyses have highlighted key mutations to guide rational drug design.

These results provide an avenue for understanding ligand modulation of the AhR functionality and for rational drug design.

Information derived from these studies will facilitate rational drug design and the selection of complementary anti-HIV drugs for combination therapy.

These structures provide a foundation for rational drug design of small molecule inhibitors to be used in prevention of invasive streptococcal disease.

In summary, this study provides insight into the ligand binding mode of GnRH1R and offers an atomic framework for rational drug design.

This technique represents a new method to assay drug translocation inside the cell and therefore incorporate rational drug design to impact antibiotic uptake.

Predicting the three-dimensional structure of ligand-receptor complexes involving G protein-coupled receptors (GPCRs) is still a challenging task in rational drug design.

This study provides new information on the three-dimensional nature of the endothelin A receptor binding site which may prove useful for rational drug design.

The contributions of quantitative structure-activity relationship (QSAR) models derived from the classical and comparative molecular field analysis (CoMFA) approaches to rational drug design were examined.