Twenty-eight patients receiving flutamide have reached twelve weeks, while 8 have reached twenty-four weeks.

This case reminds us that patients who are receiving flutamide should be regularly monitored for liver function.

Gastrointestinal toxicity was the reason for trial discontinuation in seven patients receiving flutamide and two patients receiving prednisone.

A total of 45 patients received flutamide and 328 patients received other NHT.