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Significados de significant snp em inglês
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Uso de significant snp em inglês
1
A non-zero coefficient estimate was interpreted as corresponding to a significantSNP.
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Then we preliminarily analyzed the effect of the significantSNP on intronic promoter activity.
3
SignificantSNPs should be validated in other populations to establish their potential utilization in genetic improvement programs.
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We tested the 65 most significantSNPs from the discovery sample for association in the replication sample.
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In European Americans, we identified 606 genome-wide significantSNPs representing 19 loci.
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Network analysis using partial correlations and annotation of significantSNPs can yield information about the genetic architecture of complex traits.
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We further analyzed cis-mQTL for the three most significantSNPs and 5580 potential methylation loci within these target gene regions.
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Further conditional analysis indicated that no other SNP was significantly associated with ND independent of the most-highly significantSNP, rs6474414.
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One significantSNP was associated with both seed length and seed width, and another SNP was associated with seed color.
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A total of 62 genome-wide significant and three chromosome-wide significantSNPs associated with hematological parameters were detected in this GWAS.
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Similar to previous studies, the significantSNPs in the female-stratified analysis were stronger than the significantSNPs from the sex-combined analysis.
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SNP-SNP interaction analysis of significantSNPs also showed a significant two-locus interaction model in women that was not seen in men.
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Joint association analysis of significantSNPs was then performed to assess the cumulative effect of these variants on ischemic stroke risk.
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Conclusions: Our study identified one locus having genome-wide significantSNP-by-drug interaction effect on RWT among dCCB users in comparison to ACE-I users.
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The most significantSNPs were either synonymous or situated in introns; more research is needed to uncover the underlying causal DNA variat …
16
Most current methods choose the most significantSNP from each gene as a representative, ignoring the joint action of multiple SNPs within a gene.