Significados de specific defect em inglês

The results are consistent with a specific defect in methylation of repetitive DNA sequences in human cancer.

These mutants have a specific defect in secretion from synaptic and large dense-cored vesicles [Verhage et al.

We now report the elucidation of a molecular mechanism responsible for the cell type- specific defect mediated by the rhinovirus IRES.

Multiple rearrangement architectures are present, but tandem duplications are particularly common in some cancers, perhaps reflecting a specific defect in DNA maintenance.

Selection for protection from malaria infection resulted in an erythroid- specific defect, suggesting that DARC may play a critical role in endothelial biology.

The manufacturing of ideal implants requires fabrication processes enabling an adjustment of the shape, porosity and pore sizes to the patient- specific defect.

Metabolic analysis showed that the glt1-T mutant has a specific defect in growth and glutamate biosynthesis when photorespiration was repressed by 1% CO2.

Structural and biophysical studies demonstrated specific defects in SCH772984 binding to mutant ERK.

Double-knockout mice show specific defects in the development of the hippocampus.

Here we show that loss of him-8 function causes profound X chromosome- specific defects in homolog pairing and synapsis.

Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis.

Few studies have investigated mutational specific defects; most of these assessing only activity levels from a handful of mutations using heterologous expression.

MTFMT was undetectable by immunoblot analysis of patient fibroblasts, resulting in specific defects in mitochondrial protein synthesis and assembly of the oxidative phosphorylation complexes.