Significados de staurosporine em inglês

Unlike staurosporine, though, this skeletal structure was a much simpler chemical.

These findings were confirmed by results using H-7 and staurosporine.

Similarly, endogenous PICOT was cleaved in cell death responses induced by staurosporine and etoposide.

Cell border retraction and gap formation produced by low calcium was also prevented by staurosporine.

Here, we present the structure of the human ASK1 catalytic domain in complex with staurosporine.

Such activity of extracts from EMCV-infected cells was suppressed by the protein kinase inhibitor staurosporine.

The existence of staurosporine inspired Matter.

Monitoring the effects of small-molecule ligands on the profiles delineated more than 50 targets for the kinase inhibitor staurosporine.

In contrast, the protein kinase C inhibitor staurosporine did not affect histamine release by either anti-IgE or grass pollen.

In contrast these PKA residues are either conserved or replaced by smaller ones in protein kinases highly sensitive to staurosporine inhibition.

We show in this report that treatment of only M phase-arrested mouse cells, with the protein kinase inhibitor staurosporine, induced polyploidy.

Peroxide also stimulated internalization of cadherins as measured by the trypsin protection assay, which was not blocked by staurosporine or Gö6976.

We report that although staurosporine activated Bax and the mitochondrial caspase-dependent apoptotic pathway, it also induced apoptosis of melanoma by caspase-independent pathways.

In the present study, we have examined the apoptosis-inducing potential of staurosporine in cultured melanoma cell lines and dissected the staurosporine-induced apoptotic signaling pathway.

Differentiated FSHD and unaffected cultures were both more sensitive to glutathione depletion than proliferating cultures, but showed similar responses to paraquat, staurosporine, and peroxide.

Here we show that CRP1 is induced by growth-inhibitory signals, such as increased cellular density, and cytotoxic stress induced by UV radiation or staurosporine.