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Among other effects, our computations included the stem-loop coupling and ion-ion interactions inside the stem.
2
This region forms a stable stem-loop structure in vitro.
3
In addition, these cellular proteins bind to stem-loop IV of the internal ribosomal entry site.
4
PCBP binds to stem-loop IV RNA with six-times-higher affinity than to the 5' cloverleaf structure.
5
A mutation within the stem-loop sequence reduces the rate of frameshifting by about 80%.
6
The three other mutations were introduced to disrupt the proposed stem-loop structure encompassing the editing site.
7
We present here the solution structures of a common, critical domain within each of these IRESs, stem-loop IIIc.
8
However, the steps for cloning stem-loop constructs are cumbersome requiring either multiple cloning steps or multi-fragment ligation reactions.
9
Binding of BglG prevents formation of the terminator stem-loop structure, thereby causing the RNA polymerase to continue transcription.
10
The sequence encoded the 5' untranslated flanking region of ferritin L-chain mRNA, which includes an IRE stem-loop structure.
11
We discuss potential translation initiation mechanisms for the novel ORF in the context of the IGR-IRES and 5'-adjacent stem-loop.
12
Tat exerts its function by binding a RNA stem-loop structure proximal to the viral mRNA cap site termed TAR.
13
Regions within these transcripts predicted to form stem-loop structures are processed by Microprocessor and can inhibit DNMT1-mediated methylation in vitro.
14
Sequences encoding a stem-loop structure downstream of daaE play an essential role in determining the stability of the daaE mRNA.
15
Thus, Roquin proteins act broadly as mediators of mRNA deadenylation by recognizing a conserved class of stem-loop RNA degradation motifs.
16
Putative microRNA targets were predicted for both five and three prime sequences derived from the stem-loop of the MIR gene.