Deposit of uric acid crystals, in the form of monosodium urate crystals, in people with longstanding hyperuricemia (high levels of uric acid in the blood)
1 Nearly all the tophi were of intermediate signal intensity on T1-weighted images.
2 The specificity remained high in subjects with early disease and without clinical signs of tophi .
3 Identification of tophi indicates a definitive diagnosis of gout.
4 These nodular concretions are called tophi or chalkstones.
5 The purpose of this study was to determine the MR imaging characteristics of intraosseous and soft-tissue tophi .
6 A 55-year-old woman was referred to our ward for further evaluation of marked hyperuricaemia and suspected tophi .
7 Tophi respond well to anti-hyperuricemic therapy, during which they gradually decrease in size.
8 Tophi are most often seen in tissues that have a poor blood supply and low temperature, such as the ear helix and first MP joint.
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